Check it out here.
In general we look for a new law by the following process. First we guess it. Then we compute the consequences of the guess to see what would be implied if this law that we guessed is right. Then we compare the result of the computation to nature, with experiment or experience, compare it directly with observation, to see if it works. If it disagrees with experiment it is wrong. In that simple statement is the key to science. It does not make any difference how beautiful your guess is. It does not make any difference how smart you are, who made the guess, or what his name is – if it disagrees with experiment it is wrong. That is all there is to it.
From 1964:
The remark which I read somewhere, that science is all right as long as it doesn't attack religion, was the clue I needed to understand the problem. As long as it doesn't attack religion it need not be paid attention to and nobody has to learn anything. So it can be cut off from society except for its applications, and thus be isolated. And then we have this terrible struggle to try to explain things to people who have no reason to want to know. But if they want to defend their own point of view, they will have to learn what yours is a little bit. So I suggest, maybe correctly and perhaps wrongly, that we are too polite.